Writing in Arthritis and Rheumatism, the journal of the American College of Rheumatology, researchers from the Hospital Clinic in Barcelona, Spain, have reported the results of a 7-year study on the results of total knee replacement surgery in people with severe osteoarthritis. Affecting a large number of people, especially seniors, osteoarthritis is responsible for significant cartilage loss around the joints, resulting in extreme pain and disability. As the population ages and lives longer, knee replacement becomes a viable option to maintain or regain quality of life. According to the study, while most patients were happy with the surgery’s outcome and able to engage in physical activity (a self- perpetuating benefit), women did not fare as well as men. Speculation is that women may be waiting too long into the progression of the disease to have the surgery. Also, people who are obese do not derive the same benefits as those who are near their ideal weight.